β-conglycinin combined with fenofibrate or rosuvastatin have exerted distinct hypocholesterolemic effects in rats
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چکیده
منابع مشابه
Effects of rosuvastatin and/or β-carotene on non-alcoholic fatty liver in rats
The prevalence of non-alcoholic fatty liver disease (NAFLD) has markedly increased, especially in patients exhibit one or more features of the metabolic syndrome. This study investigates the effect of rosuvastatin (RSV) and/or β-carotene (βC) in NAFLD-induced rats. Rats were classified into nine groups; normal (I), NAFLD-induced with high-fat diet (HFD; II), NAFLD switched to regular diet (RD; ...
متن کاملAdditive beneficial effects of fenofibrate combined with atorvastatin in the treatment of combined hyperlipidemia.
OBJECTIVES We compared vascular and metabolic responses (and adverse responses) to statin and fibrate therapies alone or in combination in patients with combined hyperlipidemia. BACKGROUND The mechanisms of action for statins and fibrates are distinct. METHODS Fifty-six patients were given atorvastatin 10 mg and placebo, atorvastatin 10 mg and fenofibrate 200 mg, or fenofibrate 200 mg and p...
متن کاملeffects of rosuvastatin and/or b-carotene on non-alcoholic fatty liver in rats
the prevalence of non-alcoholic fatty liver disease (nafld) has markedly increased, especially in patients exhibit one or more features of the metabolic syndrome. this study investigates the effect of rosuvastatin (rsv) and/or b-carotene (bc) in nafld-induced rats. rats were classified into nine groups; normal (i), nafld-induced with high-fat diet (hfd; ii), nafld switched to regular diet (rd; ...
متن کاملIncreased Rosuvastatin Dose versus Concomitant Fenofibrate and Rosuvastatin Therapy to Achieve Lipid Goal in Patients with Diabetes or Atherosclerosis with Metabolic Syndrome.
PUPOSE We aimed to ascertain whether increased rosuvastatin dose is non-inferior to concomitant fenofibrate and rosuvastatin therapy in patients with diabetes or atherosclerosis with metabolic syndrome. METHODS After treatment with rosuvastatin 5 mg/day for 12 weeks, 112 patients were randomly assigned to receive either 10 mg/day rosuvastatin (group A) or 80 mg/day supra-film coated fenofibra...
متن کاملBeneficial effects of β-conglycinin on renal function and nephrin expression in early streptozotocin-induced diabetic nephropathy rats.
The objective of the present study was to investigate the effects of β-conglycinin and soya isoflavones on diabetic nephropathy (DN). DN was induced by an intravenous injection of streptozotocin (25 mg/kg) in spontaneously hypertensive rats. DN rats were divided into a non-diabetic group (C, control group) and three DN groups (D, DN with control diet; B, DN+control diet with one-eighth of casei...
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ژورنال
عنوان ژورنال: Lipids in Health and Disease
سال: 2012
ISSN: 1476-511X
DOI: 10.1186/1476-511x-11-11